The Automation of Breast Ultrasonography and the Medical Time Dedicated to the Method.

In this integrative review, we aimed to describe the records of time devoted by physicians to breast ultrasound in a review of articles in the literature, in order to observe whether the automation of the method enabled a reduction in these values. We selected articles from the Latin American and Caribbean Literature in Health Sciences (LILACS) and MEDLINE databases, through Virtual Health Library (BVS), SciELO (Scientific Electronic Library Online), PubMed, and Scopus. We obtained 561 articles, and, after excluding duplicates and screening procedures, 9 were selected, whose main information related to the guiding question of the research was synthesized and analyzed. It was concluded that the automation of breast ultrasound represents a possible strategy for optimization of the medical time dedicated to the method, but this needs to be better evaluated in comparative studies between both methods (traditional and automated), with methodology directed to the specific investigation of this potentiality.

Na presente revisão integrativa, objetivamos descrever os registros de tempo dedicado pelos médicos à ultrassonografia mamária em revisão de artigos da literatura, visando observar se a automação do método possibilitou redução destes valores. Selecionamos artigos nas bases de dados Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS) e MEDLINE, através da Biblioteca Virtual em Saúde (BVS), Scientific Electronic Library Online (SciELO), PubMed e Scopus. Obtivemos 561 artigos e, após a exclusão de artigos duplicados e procedimentos de triagem, foram selecionados 9 artigos, cujas informações principais relativas à pergunta norteadora da pesquisa foram sintetizadas e analisadas. Foi concluído que a automação da ultrassonografia mamária representa uma possível estratégia de otimização do tempo médico dedicado ao método; porém, essa conclusão necessita ser melhor avaliada em estudos comparativos entre ambos os métodos (tradicional e automatizado), com metodologia direcionada à investigação específica desta potencialidade.

Aesthetic results were more satisfactory after oncoplastic surgery than after total breast reconstruction according to patients and surgeons.

INTRODUCTION: Patient satisfaction after breast cancer surgery has an impact on body image, sexual function, self-esteem, and quality of life and may differ from the perception of the attending physician. This study aimed to compare the aesthetic outcomes and satisfaction with conservative oncoplastic surgeries, mastectomies, and total breast reconstruction. METHODS: We included 760 women diagnosed with invasive breast carcinoma or phyllodes tumors who returned at least 6 months after surgery or radiotherapy at two public hospitals and a private clinic between 2014 and 2022. Data was collected prospectively from patients and retrospectively from their medical records using a specific form after obtaining their informed consent. Aesthetic outcomes and quality of life were assessed using the BREAST-Q©, Harris Scale, and BCCT.core software. Data were evaluated using the SPSS statistical software. Statistical significance was set at p < 0.05. This study was approved by the hospital ethics committees. RESULTS: A total of 405 (53.29%) partial and 355 (46.71%) total reconstructions were included. Patients who underwent partial reconstruction were older and had higher body mass index. Patients who underwent total reconstruction had larger tumors with advanced clinical and pathological stages. Clinical and surgical complications occurred more frequently in the total reconstruction group. A greater number of reparative surgeries and lipofilling procedures were required for total reconstruction. According to the BREAST-Q, the partial reconstruction group showed significantly higher levels of women's satisfaction with their breasts, the surgical outcomes, psychosocial and sexual well-being, provision of information, and the reconstructive surgeon. Only physical well-being was slightly higher in the total reconstruction group. In most cases, the results were rated good or excellent. Physicians considered partial reconstructions to have better results than total reconstructions, although this difference was not perceived by the BCCT.core software. CONCLUSION: Women who underwent partial breast reconstruction had higher levels of satisfaction in several domains, lower frequency of complications, and required fewer surgeries to complete their reconstruction than women who underwent total reconstruction. Physicians were also more satisfied with the results of partial reconstructions.

The Automation of Breast Ultrasonography and the Medical Time Dedicated to the Method / A automatização da ultrassonografia mamária e o tempo médico dedicado ao método

Abstract In this integrative review, we aimed to describe the records of time devoted by physicians to breast ultrasound in a review of articles in the literature, in order to observe whether the automation of the method enabled a reduction in these values. We selected articles from the Latin American and Caribbean Literature in Health Sciences (LILACS) and MEDLINE databases, through Virtual Health Library (BVS), SciELO (Scientific Electronic Library Online), PubMed, and Scopus. We obtained 561 articles, and, after excluding duplicates and screening procedures, 9 were selected, whose main information related to the guiding question of the research was synthesized and analyzed. It was concluded that the automation of breast ultrasound represents a possible strategy for optimization of the medical time dedicated to the method, but this needs to be better evaluated in comparative studies between both methods (traditional and automated), with methodology directed to the specific investigation of this potentiality.

Resumo Na presente revisão integrativa, objetivamos descrever os registros de tempo dedicado pelos médicos à ultrassonografia mamária em revisão de artigos da literatura, visando observar se a automação do método possibilitou redução destes valores. Selecionamos artigos nas bases de dados Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS) e MEDLINE, através da Biblioteca Virtual em Saúde (BVS), Scientific Electronic Library Online (SciELO), PubMed e Scopus. Obtivemos 561 artigos e, após a exclusão de artigos duplicados e procedimentos de triagem, foram selecionados 9 artigos, cujas informações principais relativas à pergunta norteadora da pesquisa foram sintetizadas e analisadas. Foi concluído que a automação da ultrassonografia mamária representa uma possível estratégia de otimização do tempo médico dedicado ao método; porém, essa conclusão necessita ser melhor avaliada em estudos comparativos entre ambos os métodos (tradicional e automatizado), com metodologia direcionada à investigação específica desta potencialidade.

Extreme oncoplasty: past, present and future.

Breast surgery has evolved from mastectomy to breast-conserving surgery (BCS). Breast oncoplastic surgery later emerged with the inclusion and development of techniques used in plastic surgery for breast neoplasms. Recently, a new paradigm has been considered for mastectomy candidates with large multifocal and multicentric tumours, designated extreme oncoplasty (EO), which has allowed new techniques to be applied to tumours that would have been ineligible for BCS before. There are few publications and no uniform descriptions grouping all the technical possibilities and new indications together. We performed this a review with the objective of evaluating the indications and surgeries performed in the EO context, representing a new perspective for BCS. We observed new indications as extensive microcalcifications, locally advanced breast carcinoma with partial response to chemotherapy, small to moderate-sized non-ptotic central tumours and extreme ptosis. Small breasts are able for EO since the presence of ptosis. New surgeries are reported as disguised geometric compensation, perforators flaps, local/regional flaps, latissimus dorsi miniflap and partial breast amputation. It is important to decrease barriers to oncoplastic surgery if we want to increase the use of EO and BCS rates.

Assessing variability in breast cancer management across the world: results of a questionnaire survey amongst global international experts in breast cancer management.

Background: Breast cancer is the most common cancer in women worldwide with an estimated 2.3 million breast cancer cases diagnosed annually. The outcome of breast cancer management varies widely across the globe which could be due to a multitude of factors. Hence, a blanket approach in standardisation of care across the world is neither practical nor feasible. Aim: To assess the extent and type of variability in breast cancer management across the globe and to do a gap analysis of patient care pathway. Method: An online questionnaire survey and virtual consensus meeting was carried out amongst 31 experts from 25 countries in the field of breast cancer surgical management. The questionnaire was designed to understand the variability in diagnosis and treatment of breast cancer, and potential factors contributing to this heterogeneity. Result: The questionnaire survey shows a wide variation in breast surgical training, diagnosis and treatment pathways for breast cancer patients. There are several factors such as socioeconomic status, patient culture and preferences, lack of national screening programmes and training, and paucity of resources, which are barriers to the consistent delivery of high-quality care in different parts of the world. Conclusion: On-line survey platforms distributed to global experts in breast cancer care can assess gaps in the diagnosis and treatment of breast cancer patients. This survey confirms the need for an in-depth gap analysis of patient care pathways and treatments to enable the development of personalised plans and policies to standardise high quality care.

Prognostic Role of PD-L1 Expression in Invasive Breast Cancer: A Systematic Review and Meta-Analysis.

Programmed death ligand 1 (PD-L1) has been investigated in various types of cancer; however, the role of PD-L1 expression in breast cancer remains controversial. We performed a systematic review and meta-analysis to assess the association of PD-L1 expression with clinicopathological variables, overall survival (OS), and disease-free survival (DFS) in invasive breast cancer. A total of 965 articles were included from CINAHL, Embase, PubMed, and Scopus databases. Of these, 22 studies encompassing 6468 cases of invasive breast cancer were included in the systematic review, and 15 articles were included in the meta-analysis. PD-L1 expression was associated with age ≥ 50 years, lymph node status-negative, progesterone receptor-negative, Ki67 ≥ 20%, and human epidermal growth factor receptor 2 (HER2)-negative. PD-L1 positivity was associated with worse OS (hazard ratio, HR, 2.39; 95% confidence interval, CI, 1.26-3.52; p =< 0.000); however, there was no significant improvement in DFS (HR 0.17; 95% CI -0.12-0.46; p =< 0.252). PD-L1 positivity was significantly associated with the clinicopathological characteristics of favorable and unfavorable prognoses. However, the final clinical outcome was associated with lower OS and had no significant association with DFS.

Oncoplastic Mammoplasty with disguised geometric compensation.

OBJECTIVE: To evaluate the results of a cohort of patients submitted to a new technique of oncoplastic mammoplasty, referred to as Disguised Geometric Compensation Mammoplasty (GCM), which is suitable for tumours involving the glandular tissue in the pillars of the mammoplasty. MATERIALS AND METHODS: Twenty-five breast tumours involving the pillars of the mammoplasty were included, 20 (80.0%) invasive ductal carcinomas, 3 (12.0%) phyllodes tumours, 1 (4.0%) invasive lobular carcinoma, and 1 (4.0%) in situ ductal carcinoma. Preoperative markings followed the "Wise-pattern" technique. The resection of the tumour in the pillar, preserving the overlying skin, was geometrically compensated with a corresponding area coming from the lower poles, which folded over itself and maintained the skin vascularity in the pillar. One patient was converted to classic GCM due to a positive skin margin in the frozen section. Another patient combined a Classic GCM for the inner quadrants and a Disguised GCM for the outer quadrants on the same breast. One patient decided to undergo a bilateral mastectomy after some months because of a BRCA 1 mutation. Immediate fat grafting was done in one case. Approval from the ethics committee: n. 2.322.212. RESULTS: Mean age was 47.0 ± 9.5 years. Mean clinical tumour size was 47.2 ± 22.2mm before chemotherapy and 36.7 ± 22.5mm, after. There were 11 (44.0%) locally advanced and 1 (4.00%) multicentric tumours. Nine (36.0%) were submitted to neoadjuvant chemotherapy. Adjuvant treatment was indicated according to the necessity. Ptosis was corrected in all cases. The aesthetic results were rated as excellent or good in 21 (95.5%) cases, by the Harris scale and the BCCT.core. The BREAST-Q scores for the satisfaction with the breasts and satisfaction with outcomes were 81.5 (±15.0) and 90.4 (±11.7), respectively. Intraoperative frozen sections were done in 12 (48%) cases. There was 1 (4.0%) focus of DCIS in the skin margin treated with radiotherapy. Minor complications occurred in 6 (24.0%) patients. There was 1 (4.0%) local recurrence treated with radical mastectomy, and 1 (4.0%) metastasis after 3 months. No deaths were observed within a mean follow-up time of 16.3 ± 11.4 months. CONCLUSIONS: The disguised geometric compensation mammoplasty allowed breast conservation in situations requiring large resection in the pillars of the mammoplasty, with a high rate of free margins, correction of ptosis, satisfactory symmetry, and few complications.

Should breast reconstruction and breast oncoplastic procedures be performed during the coronavirus pandemic?

The onset of the COVID-19 pandemic has changed the face of the treatment of breast cancer and breast reconstruction globally. Mastectomy with immediate implant-based breast reconstruction was on the rise due to advances in meshes and implants. However, due to the prioritisation of the critically ill and diversion of the work force, breast cancer treatment has drastically changed. This is an opinion paper written by the authors with experience and importance in the scenario of breast reconstructive surgery. The authors are from different countries with the COVID-19 pandemic in different stages.

Plagiarism in scientific publications

Plagiarism in scientific publications is a topic of fundamental importance and rarely addressed in the literature. It is associated with ethical issues that go beyond research itself, a fact that values the discussion on the topic. The concept, the main types of plagiarism, ethical relationships, preventive methodologies aiming to minimize their occurrence, diagnostic methodologies, and potential penalties involved are discussed. Every researcher and team involved in publishing articles should be aware of the importance and relevance of not plagiarizing, since being cautious about it is essential to build a solid curriculum on the part of the researcher, and credibility on the part of scientific journals.

Vitiligo as a Köebner phenomenon after oncoplastic breast surgery

The Köebner phenomenon is characterized by the appearance of several types of dermatological lesions after traumatic stimulation. The triggering of this phenomenon after breast surgery is uncommon and usually associated with psoriatic lesions. The aim of this study was to describe two cases of vitiligo as the initial manifestation of Köebner phenomenon after breast oncoplastic surgery. Case 1: female, 41 years old, no history of dermatological pathologies, presenting with tubular carcinoma in the right breast. Quadrantectomy and sentinel lymph node biopsy were performed, followed by reconstruction with mammoplasty. Later, the patient started on tamoxifen and underwent radiotherapy, without complications. Thirty days after treatment, the patient presented progressive depigmentation of the areola-papillary complex. Topical treatment was started with dermatological ointment tacrolimus monohydrate and, after one year, the condition was completely resolved. Case 2: 52-yearold woman with previous history of vitiligo on the face, with complete clinical response after dermatological treatment. She was diagnosed with ductal carcinoma in situ on the left breast and underwent quadrantectomy, by means of mammoplasty using the round block technique. Afterwards, she underwent radiotherapy and started tamoxifen. Four years after the surgery, she developed dyschromia in the ipsilateral periareolar region and was diagnosed with vitiligo. Local dermopigmentation was offered, but the patient opted for an expectant conduct and clinical follow-up. To our knowledge, this is the first description of Köebner phenomenon after breast oncoplastic surgery. In these cases, the therapeutic approach must be multidisciplinary and count on the assessment of multiple clinical and individual parameters.

Surgical breast incisions treated with 2-octyl-cyanoacrylate versus intradermal nylon suture: a randomized clinical trial. / Incisões cirúrgicas mamárias tratadas com 2-octilcianoacrilato versus sutura intradérmica com fio de nylon: ensaio clínico randomizado.

OBJECTIVE: to evaluate the safety profile and aesthetic results of 2-octyl-cyanoacrylate versus intradermal nylon suture in breast surgeries. METHODS: an open-label, randomized, clinical trial evaluating the occurrence of complications, such as dehiscence, hematoma, infection, and allergic reactions after the use of 2-octyl-cyanoacrylate or nylon thread. The size of the incisions, skin closure time, and total surgical time were also analyzed. The aesthetic outcome was evaluated at 40 and 180 days after surgery, by means of the average width of the surgical wound and by subjective conceptual assessment (optimal, good, reasonable, or poor). RESULTS: 79 patients were included: 37 in the 2-octyl-cyanoacrylate group and 42 in the nylon suture group. The study was stopped before the end of patient recruitment due to the occurrence of a greater number of dehiscences in the adhesive group (OR: 11.42; 95%CI: 1.36-96.02; p=0.007). Regarding the other analyzed complications, the surgical duration and postoperative aesthetic result, no significant differences were observed between the groups. The mean operative wound size was greater in the adhesive group than in the suture group, but there was no correlation between wound size and the largest number of dehiscences. CONCLUSION: while the cosmetic outcomes with the two techniques were similar, there was a greater risk of dehiscence with the use of 2-octyl-cyanoacrylate compared to intradermal suturing.

OBJETIVO: avaliar o perfil de segurança e os resultados estéticos do 2-octilcianoacrilato versus sutura intradérmica com fio de nylon em cirurgias mamárias. MÉTODOS: ensaio clínico randomizado, aberto, que avaliou a ocorrência de complicações, como deiscência, hematoma, infecção e reações alérgicas após o uso do 2-octilcianoacrilato ou do fio de nylon. Também foi analisado o tamanho das incisões, o tempo de fechamento da pele e o tempo cirúrgico total. O resultado estético foi avaliado após 40 e 180 dias da cirurgia, por meio da largura média da ferida operatória e por avaliação subjetiva conceitual (ótimo, bom, razoável ou ruim). RESULTADOS: foram incluídas 79 pacientes, sendo 37 no grupo 2-octilcianoacrilato e 42 no grupo de sutura com fio de nylon. O estudo foi interrompido antes do término do recrutamento dos pacientes pela ocorrência de maior número de deiscências no grupo do adesivo (OR: 11,42; IC95%: 1,36-96,02; p=0,007). Em relação às demais complicações analisadas, ao tempo cirúrgico e ao resultado estético no pós-operatório, não se observaram diferenças significativas entre os grupos. A média do tamanho da ferida operatória foi maior no grupo do adesivo em relação ao grupo da sutura, mas não houve correlação entre o tamanho da ferida e o maior número de deiscências. CONCLUSÃO: o 2-octilcianoacrilato apresentou maior risco de deiscência em relação à sutura intradérmica, com resultados estéticos equivalentes.

The cosmetic outcome of breast reconstruction: reproducibility of different methods assessed by different professionals / Resultado estético após reconstrução mamária: reprodutibilidade de diferentes métodos avaliados por diferentes profissionais

Objective: To compare the reproducibility of different methods for assessing the cosmetic outcome of breast reconstruction, which was assessed by different health professionals. Methods: Photographs of 270 breast cancer patients who had been submitted to breast reconstruction of some type were included. A plastic surgeon, a resident in plastic surgery, two mastologists, two residents in mastology, and two psychologists performed the evaluation. The modified Garbay and Harvard scales and the objective BCCT. core software program were used. Cohen's Kappa and Spearman correlation coefficients were calculated. Results: The mean age of the patients was 55.7 (±11.1) years. Overall, 145 women (53.7%) underwent partial breast reconstruction and 125 (46.3%), total breast reconstruction. The mean follow-up time was 63.7±45.6 months. By applying the Harvard scale, the interobserver reproducibility among the different professionals was minimal; whereas the Garbay scale had no agreement. The correlations between the BCCT.core software program and the Harvard and modified Garbay scales were moderate. Conclusion: Correlations between both the modified Garbay scale and the Harvard scale and the objective (BCCT.core) test were moderate. There was less interobserver variability with the Harvard scale compared to the modified Garbay scale.

Objetivo: Comparar a reprodutibilidade de métodos diferentes de avaliação dos resultados estéticos de cirurgias reconstrutivas da mama, por avaliadores distintos. Métodos: Foram incluídas fotografias de 270 pacientes portadoras de neoplasia da mama que passaram por cirurgias reconstrutivas da mama. As notas da avaliação foram dadas por um cirurgião plástico, um residente em cirurgia plástica, dois mastologistas, dois residentes em mastologia e dois psicólogos. Foram utilizadas as escalas de Harvard e Garbay modificada e a nota objetiva do programa BCCT.core. Foram calculados os índice Kappa de concordância interobservador e de correlação de Spearman. Resultados: A média de idade das pacientes foi de 55,7 anos (±11,1). No geral, 145 (53,7%) mulheres foram submetidas a tratamento conservador com cirurgia oncoplástica e 125 (46,3%) passaram por mastectomia e reconstrução total. A média de tempo de seguimento foi de 63,7±45,6 meses. Para a escala de Harvard, houve uma reprodutibilidade interobservador razoável para os diferentes profissionais, enquanto na escala de Garbay, a reprodutibilidade foi pobre entre os profissionais. De forma geral, a nota dada pelo programa BCCT.core correlacionou-se moderadamente com a escala de Harvard e a de Garbay modificada. Conclusão: As escalas de Harvard e de Garbay modificada correlacionam-se igualmente de forma moderada com o teste objetivo (BCCT.core). A escala de Harvard tem menor variabilidade interobservador, se comparada com a escala de Garbay.

Incisões cirúrgicas mamárias tratadas com 2-octilcianoacrilato versus sutura intradérmica com fio de nylon: ensaio clínico randomizado / Surgical breast incisions treated with 2-octyl-cyanoacrylate versus intradermal nylon suture: a randomized clinical trial

RESUMO Objetivo: avaliar o perfil de segurança e os resultados estéticos do 2-octilcianoacrilato versus sutura intradérmica com fio de nylon em cirurgias mamárias. Métodos: ensaio clínico randomizado, aberto, que avaliou a ocorrência de complicações, como deiscência, hematoma, infecção e reações alérgicas após o uso do 2-octilcianoacrilato ou do fio de nylon. Também foi analisado o tamanho das incisões, o tempo de fechamento da pele e o tempo cirúrgico total. O resultado estético foi avaliado após 40 e 180 dias da cirurgia, por meio da largura média da ferida operatória e por avaliação subjetiva conceitual (ótimo, bom, razoável ou ruim). Resultados: foram incluídas 79 pacientes, sendo 37 no grupo 2-octilcianoacrilato e 42 no grupo de sutura com fio de nylon. O estudo foi interrompido antes do término do recrutamento dos pacientes pela ocorrência de maior número de deiscências no grupo do adesivo (OR: 11,42; IC95%: 1,36-96,02; p=0,007). Em relação às demais complicações analisadas, ao tempo cirúrgico e ao resultado estético no pós-operatório, não se observaram diferenças significativas entre os grupos. A média do tamanho da ferida operatória foi maior no grupo do adesivo em relação ao grupo da sutura, mas não houve correlação entre o tamanho da ferida e o maior número de deiscências. Conclusão: o 2-octilcianoacrilato apresentou maior risco de deiscência em relação à sutura intradérmica, com resultados estéticos equivalentes.

ABSTRACT Objective: to evaluate the safety profile and aesthetic results of 2-octyl-cyanoacrylate versus intradermal nylon suture in breast surgeries. Methods: an open-label, randomized, clinical trial evaluating the occurrence of complications, such as dehiscence, hematoma, infection, and allergic reactions after the use of 2-octyl-cyanoacrylate or nylon thread. The size of the incisions, skin closure time, and total surgical time were also analyzed. The aesthetic outcome was evaluated at 40 and 180 days after surgery, by means of the average width of the surgical wound and by subjective conceptual assessment (optimal, good, reasonable, or poor). Results: 79 patients were included: 37 in the 2-octyl-cyanoacrylate group and 42 in the nylon suture group. The study was stopped before the end of patient recruitment due to the occurrence of a greater number of dehiscences in the adhesive group (OR: 11.42; 95%CI: 1.36-96.02; p=0.007). Regarding the other analyzed complications, the surgical duration and postoperative aesthetic result, no significant differences were observed between the groups. The mean operative wound size was greater in the adhesive group than in the suture group, but there was no correlation between wound size and the largest number of dehiscences. Conclusion: while the cosmetic outcomes with the two techniques were similar, there was a greater risk of dehiscence with the use of 2-octyl-cyanoacrylate compared to intradermal suturing.

Foreign body in the breast: multiple sewing needles / Corpo estranho no parênquima mamário: múltiplas agulhas

Needles embedded in the breast are an unusual situation. It is reported the possibility of developing an abscess and the risk of migration of the needles. We report the case of a 38 year old woman with approximately 25 needles inserted in her breasts, bilaterally. According to the patient, the insertion occurred during the episode of a recent physical aggression; however, the hypothesis of self-mutilation could not be ruled out. She also referred the withdrawal of some needles at home and tried a surgical resection of others. Physical examination of the breasts revealed bilateral bruising, located in the upper inner quadrant of the left breast and diffusely in the right breast. Ultrasound examination showed needles in both breasts, associated with a hyperechoic area between 5 and 6h of the right breast, corresponding to palpable clinical area. An X-ray and chest tomography also revealed the presence of several needles in the breasts. At mammography, multiple intra-mammary needles and lymph nodes were diffusely distributed through the parenchyma, bilaterally. After discussing with the patient about the diagnosis and therapeutic options, we opted for clinical follow-up. Currently, the patient has moderate acyclic mastalgia, and is on clinical follow up for 55 months

Agulhas inseridas no parênquima mamário constituem uma situação incomum, podendo haver ocorrência de abscessos e o risco de migração das agulhas. Descrevemos o caso de uma paciente do sexo feminino, de 38 anos de idade, diagnosticada com aproximadamente 25 agulhas de costura em suas mamas, bilateralmente. Segundo a paciente, a inserção ocorreu durante episódio de agressão física recente; porém, a hipótese de automutilação não pôde ser descartada. A paciente também referiu a retirada domiciliar de algumas agulhas e a tentativa de retirada em outro Serviço. Ao exame físico das mamas, evidenciava-se equimose bilateral, localizada no quadrante súpero-medial da mama esquerda e difusamente na mama direita. O exame ultrassonográfico evidenciou agulhas em ambas as mamas, associadas à área hiperecoica entre 5 e 6h da mama direita, correspondente a área clínica palpável. A radiografia e a tomografia de tórax visibilizaram a presença de vários corpos estranhos nas mamas, de aspecto metálico, compatíveis com agulhas. Após discussão com a paciente acerca do diagnóstico e das opções terapêuticas, optou-se por conduta expectante. Após 55 meses, a paciente refere mastalgia acíclica moderada e mantém seguimento clínico no Serviço

Oncoplastic Breast Consortium consensus conference on nipple-sparing mastectomy.

PURPOSE: Indications for nipple-sparing mastectomy (NSM) have broadened to include the risk reducing setting and locally advanced tumors, which resulted in a dramatic increase in the use of NSM. The Oncoplastic Breast Consortium consensus conference on NSM and immediate reconstruction was held to address a variety of questions in clinical practice and research based on published evidence and expert panel opinion. METHODS: The panel consisted of 44 breast surgeons from 14 countries across four continents with a background in gynecology, general or reconstructive surgery and a practice dedicated to breast cancer, as well as a patient advocate. Panelists presented evidence summaries relating to each topic for debate during the in-person consensus conference. The iterative process in question development, voting, and wording of the recommendations followed the modified Delphi methodology. RESULTS: Consensus recommendations were reached in 35, majority recommendations in 24, and no recommendations in the remaining 12 questions. The panel acknowledged the need for standardization of various aspects of NSM and immediate reconstruction. It endorsed several oncological contraindications to the preservation of the skin and nipple. Furthermore, it recommended inclusion of patients in prospective registries and routine assessment of patient-reported outcomes. Considerable heterogeneity in breast reconstruction practice became obvious during the conference. CONCLUSIONS: In case of conflicting or missing evidence to guide treatment, the consensus conference revealed substantial disagreement in expert panel opinion, which, among others, supports the need for a randomized trial to evaluate the safest and most efficacious reconstruction techniques.

ONCOPLASTIC MAMMOPLASTY WITH GEOMETRIC COMPENSATION TECHNIQUE IN AN OLDER ADULT PATIENT / Mamoplastia oncoplástica com técnica de compensação geométrica em paciente idosa

Breast cancer is a neoplasm of high incidence in women, which has been increasingly affecting older adult patients. Conservative breast surgery has changed the history of Mastology. Oncoplastic techniques and breast reconstruction are used in pursuit of better harmony between oncological treatment and cosmetic results. This study reports the case of an older adult patient submitted to oncological mammoplasty with geometric compensation technique

O câncer de mama é uma neoplasia de grande incidência nas mulheres e cada vez mais tem se apresentado em pacientes idosas. A cirurgia conservadora de mama alterou definitivamente a história da mastologia. As técnicas de oncoplastia e reconstrução mamária são utilizadas buscando uma maior sintonia entre o tratamento oncológico e o resultado estético. Este estudo relata o caso de paciente idosa submetida à mamoplastia oncológica com técnica de compensação geométrica.

ONCOPLASTIC SURGERY IN CONSERVATIVE SURGICAL TREATMENT OF LOCALLY ADVANCED BREAST CANCER: A SYSTEMATIC REVIEW / Cirurgia oncoplástica no tratamento cirúrgico conservador do câncer de mama localmente avançado: uma revisão sistemática

Introduction: Breast cancer conservative surgical treatment has become standard procedure as it reduces mutilation and preserves the body self-image. Advances in adjuvancy have increased its indications for larger tumors, and recent studies have been demonstrating its safety in locally advanced cases. Objective: To evaluate the role of oncoplastic surgery in the conservative surgical treatment of locally advanced breast cancer. Method: This is a systematic review. Out of the 523 studies found in the PubMed electronic database published between 2012 and 2017 using the keywords "breast cancer" and "oncoplastic surgery", we selected 12 that dealt specifically with the topic. Results: No randomized trial was found. Most series were retrospective. The average initial tumor size ranged between 40 and 67.0 mm. The conversion rate from mastectomy to conservative treatment varied from 34 to 72.3%. Wise pattern was the most used technique. Oncoplastic surgery produced a greater amount of excised breast tissue. The oncoplastic technique did not differ from the standard conservative treatment concerning positive margins. Oncoplastic techniques showed higher rates of surgical complications but did not delay adjuvancy. Locoregional recurrence and overall survival ranged from 0 to 14.6% and 76.7 to 86.6%, respectively. Patients considered the cosmetic results acceptable in 84 to 92.3% of the cases. Conclusion: Oncoplastic surgical techniques allow a higher rate of breast conservation in locally advanced cancer, without apparent compromise of oncological safety.

Introdução: O tratamento cirúrgico conservador do câncer de mama se tornou o tratamento padrão por reduzir a mutilação e preservar a autoimagem corporal. Os avanços na adjuvância ampliaram as indicações para tumores maiores e novos trabalhos vêm demostrando segurança nos casos localmente avançados. Objetivo: Avaliar o papel da cirurgia oncoplástica no tratamento cirúrgico conservador do câncer de mama localmente avançado. Métodos: Revisão sistemática. Entre os 523 trabalhos encontrados na base de dados eletrônica PubMed entre 2012 e 2017 utilizando as palavras-chave "breast cancer" e "oncoplastic surgery", foram selecionados 12 trabalhos que tratavam especificamente do tema. Resultados: Nenhum estudo randomizado foi encontrado. As maiores séries foram retrospectivas. A média de tamanho tumoral inicial variou entre 40 e 67,0 mm. A taxa de conversão de mastectomia para tratamento conservador variou de 34 a 72,3%. Wise pattern foi a técnica mais utilizada. Foi observada maior quantidade de ressecção de tecido mamário quando a cirurgia oncoplástica foi realizada. Não foi observada diferença em relação ao comprometimento de margem quando se comparou a técnica oncoplástica com o tratamento conservador padrão. Técnicas oncoplásticas apresentaram maiores índices de complicações cirúrgicas, porém isso não acarretou atraso na adjuvância. A recorrência locorregional e a sobrevida global variaram de 0 a 14,6% e de 76,7 a 86,6%, respectivamente. Os resultados cosméticos foram considerados aceitáveis pelas pacientes em 84 a 92,3% dos casos. Conclusões: Técnicas cirúrgicas oncoplásticas permitem maior taxa de conservação da mama no cenário do câncer localmente avançado, sem aparente comprometimento da segurança oncológica

Complete axillary dissection without drainage for the surgical treatment of breast cancer: a randomized clinical trial.

OBJECTIVE:: This randomized clinical trial evaluated the possibility of not draining the axilla following axillary dissection. METHODS:: The study included 240 breast cancer patients who underwent axillary dissection as part of conservative treatment. The patients were divided into two groups depending on whether or not they were subjected to axillary drainage. ClinicalTrials.gov: NCT01267552. RESULTS:: The median volume of fluid aspirated was significantly lower in the axillary drainage group (0.00 ml; 0.00 - 270.00) compared to the no drain group (522.50 ml; 130.00 - 1148.75). The median number of aspirations performed during conservative breast cancer treatment was significantly lower in the drainage group (0.5; 0.0 - 4.0) compared to the no drain group (5.0; 3.0 - 7.0). The total volume of serous fluid produced (the volume of fluid obtained from drainage added to the volume of aspirated fluid) was similar in the two groups. Regarding complications, two cases (2.4%) of wound dehiscence occurred in the drainage group compared to 13 cases (13.5%) in the group in which drainage was not performed, with this difference being statistically significant. Rates of infection, necrosis and hematoma were similar in both groups. CONCLUSION:: Safety rates were similar in both study groups; hence, axillary dissection can feasibly be performed without drainage. However, more needle aspirations could be required, and there could be more cases of wound dehiscence in patients who do not undergo auxiliary drainage.

TRENDS AND ATTITUDES TOWARD ONCOPLASTICS TRAINING IN MASTOLOGY IN BRAZIL / Tendências e atitudes para o treinamento oncoplástico em Mastologia no Brasil

Introduction: There is a growing interest in, and an increasing demand for, oncoplastic (OP) and reconstructive surgery training by breast surgeons. However, until now there has been a lack of a specific model for training in this field in most countries and no data with respect to learning curves. Mastology has been a medical specialty in Brazil since 1978. It is fully dedicated to studying, preventing, diagnosing, and managing all diseases of the breast. Incorporation of OP and reconstructive surgery in Mastology presents a number of challenges, and there are some controversial issues to overcome. Objective: The purpose of this study, therefore, was to analyze how OP and reconstructive techniques are being incorporated into surgical training in Mastology in Brazil. Methods: A specific survey was designed to cover all surgical residents who concluded their regular program in Mastology in Brazil in 2015 and 2016. Results: One hundred twenty-four residents from 49 breast units were included, with the majority having their training for all 2 years of their residence, as recommended by the Brazilian Society of Mastology. In addition, most of the respondents were able to perform partial breast reconstructions and reconstructions using expanders and implants, but 20% of them had a lack of specific training in these techniques. Conclusion: As adequate local control of disease and quality of life are related to surgical decisions, it is expected that breast surgeons expand their limits and responsibilities in order improve the reality of most breast cancer patients.

Introdução: Existe um interesse e uma demanda crescente de treinamento oncoplástico (OP) e cirurgia reconstrutiva por cirurgiões de mama. No entanto, até agora tem faltado um modelo específico de treinamento neste campo na maioria dos países, sem dados com relação à curva de aprendizado. A Mastologia tem sido uma especialidade médica no Brasil desde 1978. É totalmente dedicada a estudar, prevenir, diagnosticar e gerenciar todas as doenças da mama. A incorporação de OP e cirurgia reconstrutiva na Mastologia apresenta uma série de desafios, e há algumas questões controversas a serem superadas. Objetivo: O objetivo deste estudo, portanto, foi analisar como a OP e as técnicas reconstrutivas estão sendo incorporadas no treinamento cirúrgico em Mastologia no Brasil. Métodos: uma pesquisa específica foi projetada para cobrir todos os residentes cirúrgicos que concluíram seu programa regular em Mastologia no Brasil em 2015 e 2016. Resultados: Foram incluídos 124 residentes de 49 unidades mamárias, com a maioria treinada durante todos os 2 anos de residência, conforme recomendado pela Sociedade Brasileira de Mastologia. Além disso, a maioria dos entrevistados foi capaz de realizar reconstruções e reconstruções mamárias parciais usando expansores e implantes. Mas ainda 20% deles apresentaram falta de treinamento específico nestas técnicas. Conclusão: uma vez que o controle local adequado da doença e da qualidade de vida está relacionado às decisões cirúrgicas, espera-se que os cirurgiões de mama ampliem seus limites e responsabilidades para melhorar a realidade da maioria dos pacientes com câncer de mama.